MDGA1 (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

MDGA1

Caption

Model of MDGA1 action on Neuroligin-2-mediated inhibitory synapse organization. Neuroligins' postsynaptic membrane tran-synaptically interact with presynaptic Neurexins for synaptic development. MDGA1 (Red, Yellow and Blue) suppresses the development of inhibitory synapses by blocking the physical access of Neuroligin-2 (Cyan) to presynaptic neurexin1-β(Orange).

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KAIST

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