Striatal Neurons Generated from Corrected iPSCs (IMAGE)

Buck Institute for Research on Aging

Striatal Neurons Generated from Corrected iPSCs

Caption

Huntington's disease results in massive loss of cells in the brain, particularly in regions called the cortex and striatum. The cells depicted are from a patient with HD - they have been genetically corrected. These are striatal neurons which are expressing DARPP-32 and beta-III-tubulin, markers of neurons lost in HD.

Credit

Ellerby lab, Buck Institute

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