Deletion of Genomic DNA by Paired CRISPR (IMAGE) Center for Genomic Regulation Caption Cas9 proteins (scissors) are guided to their target sites by single guide RNAs (sgRNAs, orange ribbons). The target region in between is removed. CRISPETa software enables researcher to design such deletion experiments quickly and conveniently. Credit Pulido-Quetglas et al. CCBY Usage Restrictions CCBY License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.