Excess Noise Characterization Helps to Improve Visible Light Optical Coherence Tomography (OCT) (IMAGE)
Caption
a, The excess noise measured by a spectrometer is the superposition integral of the input excess noise and the spectrometer impulse response, which describes the spectral resolution. Excess noise correlations thus provide a simple way to assess spectral resolution of spectrometers, with appropriate assumptions. b, Visible light OCT spectrometers, aligned with the aid of excess noise correlations, show nearly uniform axial resolution versus imaging depth. The human imaging system shows only 3.4 decibel (dB) sensitivity rolloff over the first millimeter of imaging depth in air. Resulting mouse (c) and human (d) retinal images show fine outer retinal details, while revealing a very subtle outer retinal band (red arrow) in the mouse (c).
Credit
by Aaron M. Kho, Tingwei Zhang, Jun Zhu, Conrad W. Merkle, Vivek J. Srinivasan
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