Schematic Depiction (IMAGE)
Caption
Schematic depiction of the mode of action for targeted alpha radiation in skin cell-derived cancers. Cancer cells (brown) are associated with several other cell types in the tumor microenvironment, such as fibroblasts (blue). 225Ac-FAPI-04 (red) is localized to the cancer through its binding to fibroblasts, resulting in targeted irradiation of the tumor.
Credit
Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine
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