Schematic Depiction (IMAGE) Osaka University Caption Schematic depiction of the mode of action for targeted alpha radiation in skin cell-derived cancers. Cancer cells (brown) are associated with several other cell types in the tumor microenvironment, such as fibroblasts (blue). 225Ac-FAPI-04 (red) is localized to the cancer through its binding to fibroblasts, resulting in targeted irradiation of the tumor. Credit Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.