PEX2 is the E3 Ubiquitin Ligase Required for Pexophagy During Starvation (IMAGE)
Caption
Peroxisomes are degraded and PEX2 protein levels elevated in a mouse model of amino acid starvation. Mice were fed a control diet containing 18 percent protein (wt/wt) or a protein-restriction diet containing 1 percent protein (wt/wt). Representative images of fluorescent immunohistochemistry images thin slices of the livers stained with PMP70 (green) or DAPI (blue) as a marker of the nucleus. Images from two different mice for each diet conditions are shown. Bars, 20 μm. This image appears in The Journal of Cell Biology study by Sargent et al.
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© 2016 Sargent et al.
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