Figure 1. LC3 lipidation is essential for TFEB activation. (IMAGE)

The University of Osaka

Figure 1. LC3 lipidation is essential for TFEB activation.

Caption

TFEB is localized to the nucleus upon lysosomal damage in WT cells, while ATG7 KO cells, in which LC3 lipidation is defective, show impaired TFEB nuclear localization.

Credit

Osaka University

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