Reaction Pathway (IMAGE) Institute for Basic Science Caption Oxidation of the metal (M, iridium, blue pathway) leads to a 19 kcal/mol decrease in reaction's energy barrier, and allows the arylation to occur at room temperature. Credit IBS, published in Nature Chemistry Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.