Malfunctioning Gene Associated with Lou Gehrig's Disease Leads to Nerve-Cell Death in Mice (1 of 2) (IMAGE)

University of Pennsylvania School of Medicine

Malfunctioning Gene Associated with Lou Gehrig's Disease Leads to Nerve-Cell Death in Mice (1 of 2)

Caption

Neurons expressing the ALS-associated human protein TDP-43 (green) show an absence of normal TDP-43 protein (red). Virginia Lee and colleagues have shown that pertubation of normal TDP-43 expression is linked to neuron death.

Credit

Edward Lee, M.D., Ph.D.; University of Pennsylvania School of Medicine

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