CMT Structure (IMAGE)

Scripps Research Institute

CMT Structure

Caption

The new Scripps Research study found a common feature of genetic mutations causing Charcot-Marie-Tooth disease (CMT) type 2D. This image shows hotspots on the enzyme GlyRS (gold) opened up by CMT-causing mutations. The other subunit of the GlyRS dimer is shown in ribbon (cyan).

Credit

The Yang Laboratory

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