Molecular Probes Fibronectin ECM (IMAGE)

Georgia Institute of Technology

Molecular Probes Fibronectin ECM

Caption

Molecular probes displaying the LNLPHG and RFSAFY peptide sequences showed the greatest binding affinity to fibronectin fibers and the greatest efficiency in discriminating between relaxed and strained fibers. On extracellular matrix assembled by primary lung fibroblasts, LNLPHG preferentially attached to relaxed fibronectin fibers (top row), whereas RFSAFY bound to strained fibers (bottom row). (The scale bar is 20 microns)

Credit

Georgia Tech/Thomas Barker

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