ApoE4 Weakens the Blood-Brain Barrier in Mice (IMAGE)

NIH/National Institute of Neurological Disorders and Stroke

ApoE4 Weakens the Blood-Brain Barrier in Mice

Caption

Destructive enzymes (shown in green) become more active and weaken the blood-brain barrier in mice that are genetically engineered to produce only human ApoE4 (right), rather than mouse ApoE (left).

Credit

Robert Bell, Ph.D., University of Rochester Medical Center, New York.

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Please credit Robert Bell, Ph.D., University of Rochester Medical Center, New York.

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