Macrophage-mediated Vascular Bursting (IMAGE)
Caption
In this illustration based on in vivo microscopy, a tumor-associated macrophage (green) induces a burst of leakage from a tumor blood vessel (red), which releases nanoparticles into the tumor tissue (yellow). The large arrow shows nanoparticles being taken up by the macrophage, while the small dashed arrow depicts how the macrophage elicits further nanoparticle delivery via vascular bursting.
Credit
Miles Miller, PhD, and Ralph Weissleder, MD, PhD; Center for Systems Biology, Massachusetts General Hospital
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