The Loss of Dystrophin (Green) Results in Profound Defects in Muscle Stem Cells (Red) (IMAGE)

The Ottawa Hospital

The Loss of Dystrophin (Green) Results in Profound Defects in Muscle Stem Cells (Red)

Caption

A normal mouse muscle fiber (top left) is contrasted with a muscle fiber from a mouse model of Duchenne muscular dystrophy (bottom right). In normal mice, stem cells (pink) express dystrophin (green) and are able to easily generate new muscle fibers, but in the disease model, there is no dystrophin and the stem cells lose their sense of direction and have trouble generating new muscle fibers. Reproduced with permission of Will Wang.

Credit

Will Wang

Usage Restrictions

Only for use in conjunction with stories about this research.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.