Finding Which Cancers Respond to Which Drugs (IMAGE)

Cold Spring Harbor Laboratory

Finding Which Cancers Respond to Which Drugs

Caption

Organoids grown from 66 pancreatic cancer patients were exposed, one by one, to 5 standard-of-care chemotherapy drugs. After demonstrating that each organoid faithfully replicates the tumor from which it has been derived, researchers at CSHL measured the responsiveness of each organoid to each drug. For the four drugs shown here, a range of responses is indicated. Dots in the red-shaded area indicate the 33% of the the total set that most resisted the treatment; dots in the blue-shaded area represent the 33% that were most responsive. This pharmacotyping should enable doctors to start patients on treatments most likely to help them.

Credit

Tuveson Lab, CSHL

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