Coating for Amyloid (IMAGE)
Caption
Clear strands of toxic aggregated amyloid beta peptides, a hallmark of Alzheimer's disease, interact with proteins such as the anti-oxidant enzyme catalase, shown in red. The interaction disables catalase, resulting in oxidative damage to neural cells in culture. Protein-resistant coating (blue) on the aggregated amyloids inhibit these harmful interactions and protect of cells from amyloid beta-induced oxidative stress and toxicity.
Credit
Christopher Burke for UC San Diego
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For illustration of reports on this specific research finding. For other permissions, please contact scinews@ucsd.edu.
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