Illustration of Mouse Hearts that Lack Stress Hormone Receptors (IMAGE)

NIH/National Institute of Environmental Health Sciences

Illustration of Mouse Hearts that Lack Stress Hormone Receptors

Caption

Without the glucocorticoid receptor (GR), the mouse heart is enlarged, and the animal eventually has heart failure (top). However, a heart that lacks the mineralocorticoid receptor (MR)(middle) or both receptors (bottom) functions normally.

Credit

NIEHS

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