A Merger Between Photoredox and Nickel Catalysis (IMAGE)

Princeton University

A Merger Between Photoredox and Nickel Catalysis

Caption

Princeton University researchers merged two powerful areas of research to enable an unprecedented chemical reaction that neither could broadly achieve on its own. The resulting bond formation could provide an excellent shortcut for chemists as they construct and test thousands of molecules to find new drugs. In the transformation, a carboxylic acid (left) reacts with an aryl halide (right) in the presence of tiny amounts of an iridium photocatalyst and a nickel catalyst to form a direct and unique bond between two highly prevalent classes of molecules.

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(Image courtesy of Science/AAAS)

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