Tethered Toxin (IMAGE)

University of California - Irvine

Tethered Toxin

Caption

The tethered toxin (T-HmK) is drawn free and bound to a potassium channel (blue) expressed in the cell membrane. The reaction volume that a T-HmK can visit (two-headed arrow) is determined by the combined lengths of the flexible peptide linker, the GPI anchor, and the diameter of HmK toxin. The lower panel shows the expression construct design.

Credit

UCI School of Medicine

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