Dr James Murphy and Dr Isabelle Lucet, Walter and Eliza Hall Institute (IMAGE)
Caption
Dr James Murphy and Dr Isabelle Lucet at the Walter and Eliza Hall Institute and colleagues have created the first three-dimensional image of a key protein known to be involved in the development of blood and other cancers. The discovery showed the protein, called Trib1, plays a vital role in controlling how and when other proteins are degraded, which is essential for managing protein levels in the cell. The finding could be used to develop new drugs to treat cancers such as leukaemia, caused by malfunctioning of the Trib1 protein.
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Walter and Eliza Hall Institute
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