Presenilin and Its Effect on Traffic in Neurons (IMAGE)

University at Buffalo

Presenilin and Its Effect on Traffic in Neurons

Caption

Expression of human APP in fly larval nerves causes neuronal blockages (arrows, top panel) which are rescued by reductions in presenilin. Expression of human APP in fly larval brains causes cell death (arrows, bottom panel) which are rescued by reductions in presenilin.

Credit

Shermali Gunawardena

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