Small-Molecule SIK Inhibitor Induces Tanning in Human Skin Sample (IMAGE)

Massachusetts General Hospital

Small-Molecule SIK Inhibitor Induces Tanning in Human Skin Sample

Caption

Cultured human skin treated for eight days with a small-molecule SIK inhibitor (right) shows a significant increase in pigmentation. Areas treated with a control substance (left) or an SIK inhibitor less able to penetrate human skin (center) show no darkening.

Credit

Nisma Mujahid and David E. Fisher, MD, PhD, Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital

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