Crystal Structure of HIV Protein Tat (IMAGE)

University of Iowa Health Care

Crystal Structure of HIV Protein Tat

Caption

A University of Iowa and University of Nebraska study has revealed the structure of an important HIV protein attached to the human protein that the virus hijacks during infection. The structural information might help researchers develop drugs that disrupt HIV replication. Image shows structure of HIV Tat protein (red) bound to human P-TEFb protein (beige and green) superimposed on artist’s rendition of HIV viruses.

Credit

Tahir Tahirov, University of Nebraska Medical Center, and Narmin Tahirova, University of Nebraska at Lincoln.

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