Feedback from the Olfactory Cortex Spurs Sparse, Precise Responses in the Olfactory Bulb (IMAGE)

Cold Spring Harbor Laboratory

Feedback from the Olfactory Cortex Spurs Sparse, Precise Responses in the Olfactory Bulb

Caption

Fluorescent microscopy by Albeanu Lab (left image) shows activation in synaptic boutons -- communication junctions - located less than one-tenth of a millimeter beneath the surface of the olfactory bulb of an awake mouse responding to a panel of 20 odorants. Graph (right) shows that individual boutons (whose numbers correspond to circled boutons in the image) respond to a small fraction of the 20 odors, and that even adjacent boutons, like numbers 27 and 140 -- respond to different odors and in different ways (red bars indicate the bouton's activity is enhanced relative to baseline or resting state; blue bars indicate less activity relative to baseline).

Credit

Albeanu Lab, CSHL

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