Extracellular perineuronal net matrices enmesh neurons (IMAGE)

University of Washington School of Medicine/UW Medicine

Extracellular perineuronal net matrices enmesh neurons

Caption

Glucoregulatory neurons within the hypothalamic arcuate nucleus-median eminence of the brain are enmeshed by extracellular matrices known as perineuronal nets that can profoundly impact neuronal function. Latest findings implicate these structures in both brain control of glucose homeostasis and as potential targets for diabetes treatment.

Credit

Courtesy of KImberly Alonge/Schwartz Lab/UW Medicine Diabetes Research Institute

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