Plasma Activated Ringer's Lactate Solution Exhibited Anti-Tumor Effects in vitro and in vivo (IMAGE)

Nagoya University

Plasma Activated Ringer's Lactate Solution Exhibited Anti-Tumor Effects in vitro and in vivo

Caption

We created plasma-activated Ringer's lactate solution (PAL) and investigated its anti-tumor effects on cancer cells. We detected an apoptotic marker, cleaved Caspase3/7 in PAL-treated glioblastoma cells, suggesting that PAL induced apoptosis. We created a mouse xenograft model in which SiHa cervical cancer cells were injected into mice subcutaneously, and the resultant tumors were treated with PAL three times a week for six weeks. PAL effectively reduced tumor volumes.

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Nagoya University

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