Mitophagy (IMAGE)

University of Pennsylvania School of Medicine

Mitophagy

Caption

Mouse fibroblast shows Clec16a (red), the lysosome protein Lamp1 (green), the autophagosome protein LC3 (blue), and DNA (gray). The yellow overlap of the red and green stains shows that Clec16a resides in the endolysosomal compartment, part of the cellular disposal system used in mitophagy.

Credit

Scott Soleimanpour, M.D. (University of Michigan Medical School) and Doris Stoffers, M.D., Ph.D. (Perelman School of Medicine)

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