Vaccine induces a cross-reactive antibody response to multiple coronaviruses (IMAGE)

California Institute of Technology

Vaccine induces a cross-reactive antibody response to multiple coronaviruses

Caption

This new vaccine prototype works by attaching many protein fragments (specifically, receptor-binding domains or RBDs) to an engineered protein-based nanoparticle. The study, in mice, showed that the vaccine induced the production of antibodies that are broadly reactive to a wide range of coronaviruses. RBDs are particularly important for a virus to be able to infect a cell, so antibodies that recognize RBDs are likely more effective at preventing bad infections.

Credit

Courtesy of A. Cohen via BioRender

Usage Restrictions

Please use image credit

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.