MEMORY 1 (IMAGE)
Caption
Researchers at Rice University modeled the binding structures of actin and associated proteins they believe are responsible for the formation of longterm memory. Here, the beta hairpin form of zipper sequence is a potential core for the formation of intramolecular beta sheets. In the predicted complex structure of F-actin and three PRD+ABD constructs shown above, the three PDB+ABD constructs are shown in rainbow color, from blue to red, from N-terminal to C terminal. The surfaces of first 4 negative residues of actin mono-mers are colored in red and the surfaces of the two positive ends of the zipper sequence is colored in blue.
Credit
Center for Theoretical Biological Physics/Rice University
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