In Highly Lethal Type of Leukemia, Cancer Gene Predicts Treatment Response (IMAGE)

WashU Medicine

In Highly Lethal Type of Leukemia, Cancer Gene Predicts Treatment Response

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New research led by Washington University School of Medicine in St. Louis shows that patients with acute myeloid leukemia (AML) whose cancer cells carry TP53 mutations -- a feature that correlates with an extremely poor prognosis -- may live longer if they are treated with decitabine, a less intensive chemotherapy drug. The study's first author, John Welch, M.D., PhD, is pictured with Phillip Houghton, who is being treated for AML.

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Washington University

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