Hajdu-Cheney Mouse Femur (IMAGE)

University of Connecticut

Hajdu-Cheney Mouse Femur

Caption

The picture shows a cross-section of the femur of a mouse. The white and purple cells are bone marrow, the pink area is bone, and the arrows show osteoclasts resorbing bone. This mouse has too many osteoclasts; it has a variant of the NOTCH2 gene that causes a disease akin to Hajdu-Cheney syndrome in humans.

Credit

Stefano Zanotti/Canalis Lab, UConn Health

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