New Mouse Model of Depression (IMAGE)
Caption
The chimeric mouse on the left is made up of a mixture of normal (white) cells and mutant (black) cells as reflected in the variation in its fur color. The chimera is the father of the first MDD (major depressive disorder) mouse shown on the right. The MDD mouse has been engineered to contain a rare mutation that typically leads to MDD in people who inherit it, and provides a new model to study the brain mechanism that leads to this common and debilitating illness.
Credit
Zubenko, GS, Hughes III HB. Am J Med Genet Part B, 2011. copyright © 2011 Wiley-Liss, Inc
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