Loose End after Cas9 binding (IMAGE)

University of California - Berkeley

Loose End after Cas9 binding

Caption

A view of the Cas9 protein (red and blue) bound to a double strand of DNA (purple and grey). After both strands are cut, one DNA strand (purple dots) is free and able to bind with a piece of DNA to be inserted at the break.This behavior can be utilized to significantly boost the efficiency of gene editing.

Credit

Christopher Richardson, UC Berkeley

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