TDP-43, UC San Diego School of Medicine (IMAGE) University of California - San Diego Caption Left: Normal human neuroglioma cell line. Middle: Cells exposed to the toxin arsenite, an example of cellular stress, get clumps of the protein TDP-43 (colored red). Right: When arsenite-exposed cells are treated with the chemical compound mitoxantrone, TDP-43 no longer clumps. Credit UC San Diego Health Sciences Usage Restrictions Use caption and credit as indicated License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.