Heterochromatin Domains Visualized in Embryonic Stem Cells (IMAGE)

Babraham Institute

Heterochromatin Domains Visualized in Embryonic Stem Cells

Caption

A fluorescent microscopy image of mouse embryonic stem cell nuclei with heterochromatin domains localized in red (using an anti-H3K9me3 antibody) and levels of the stem cell factor NANOG revealed by the intensity of the white signal (using an anti-NANOG antibody). Nuclei with higher NANOG levels tend to have fewer and larger heterochromatin domains, which is one indicator of an open and uncompacted genome organization.

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Babraham Institute

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