SARS m6a (IMAGE)

University of California - San Diego

SARS m6a

Caption

Human enzyme METTL3 adds methyl groups to introduce m6A in SARS-CoV-2's RNA. That modification prevents the virus' RNA from triggering inflammatory molecules known as cytokines. METTL3 also leads to increased expression of pro-viral genes -- those that encode proteins needed for SARS-CoV-2 replication and survival.

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UC San Diego Health Sciences

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