Chromosomes in Colon Cancer Cells Showing Multiple Copies of the BRAF Gene (IMAGE)

Babraham Institute

Chromosomes in Colon Cancer Cells Showing Multiple Copies of the BRAF Gene

Caption

Gene amplification has been use by the cells as a mechanism to overcome MEK1/2 inhibition of growth. Red dots show the location of each chromosome's centromere. The clusters of green dots represent copies of the BRAF gene within a chromosome (green dots clustering around a single red dot).

Credit

Matthew Sale, Babraham Institute

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