Mouse neural tube (IMAGE) The Company of Biologists Caption A developing mouse neural tube. Hedgehog signalling is required to produce different types of neuronal progenitor cells, indicated by the different colours. THC inhibits Hedgehog signalling in genetically susceptible mice, leading to developmental defects, including in the neural tube. Credit Lo, H.-F., Hong, M., Szutorisz, H., Hurd, Y.L., Krauss, R.S. (2021). Δ9-Tetrahydrocannabinol inhibits Hedgehog-dependent patterning during development. Development, 148, dev199585. doi:10.1242/dev.199585 Usage Restrictions Please reference the research article. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.