Neurons and medulloblastoma cells (IMAGE)
Caption
The image depicts neurons (green) in co-culture with medulloblastoma cells (red). Phenotypically, two contrasting cell types - the former normal and quiescent, while the latter cancerous and proliferating. Martirosian et al., through the perspective of cancer neuroscience, now provide evidence that rare cells in this pediatric brain tumor masquerade like quiescent neurons and exploit a neurotransmitter metabolic pathway to survive in the cerebrospinal fluid and promote leptomeningeal metastases.
Credit
Vahan Martirosian, Josh Neman
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