Shedding Light on Sertoli Cell Function (IMAGE) Cincinnati Children's Hospital Medical Center Caption Sertoli cells are highly polarized cells that nurture different stages of germ cells at the same time. This image reveals how a single Sertoli cell, which is genetically labeled with yellow fluorescent protein among other Sertoli cells in red, contacts a number of cells in the tubule. Scientists at Cincinnati Children’s have uncovered a critical role for the Rho GTPase CDC42 in regulating the polarity of Sertoli cells and maintaining steady-state sperm production. Credit Cincinnati Children's Usage Restrictions none License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.