Alpha-synuclein Forms Lewy Body-like Inclusions (IMAGE)

University of Pennsylvania School of Medicine

Alpha-synuclein Forms Lewy Body-like Inclusions

Caption

Alpha-synuclein forms Lewy Body-like inclusions in the cytoplasm of yeast (left), but these are dissolved and alpha-synuclein returns to the plasma membrane upon expression of an engineered Hsp104 variant.

Credit

James Shorter, Ph.D., Perelman School of Medicine, University of Pennsylvania; <i>Cell</i>

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