A 'Molecular Map' of Early Mammalian Gastrulation (IMAGE)

University of Cambridge

A 'Molecular Map' of Early Mammalian Gastrulation

Caption

Each dot represents a single cell in the developing embryo, with the number of specialized cells increasing across the 48hrs from embryonic day 6.5 to embryonic day 8.5. The dots are colored based on which major cell type they represent, such as heart, lungs, brain and gut. The 116,000 dots are arranged so that cells with similar genetic activity are close to each other. This new Molecular Map is freely available to researchers to give them access to the complete genetic programs that drive the development of all major organ systems, and opens up new avenues for regenerative medicine and drug development.

Credit

Wellcome-MRC Cambridge Stem Cell Institute

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