How to Make Lung (IMAGE)
Caption
This shows normal and separate expression of Nkx2.1 (green) in lung endoderm and p63 (red) in esophagus endoderm (arrow) (Panel U). Activation of Wnt/beta-catenin results in reprogramming of esophagus endoderm to Nkx2.1 positive lung endoderm (panel V, arrow).
Credit
Edward Morrisey, PhD, University of Pennsylvania School of Medicine; Developmental Cell
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