Visualizing Metabolism in Precancerous Tissue (IMAGE)

Tufts University

Visualizing Metabolism in Precancerous Tissue

Caption

Optical fluorescence scans of excised cervical epithelial tissue. In these images, the redox ratio of coenzymes NAD/NADH and FAD/FADH show up in distinctive color hues. Sections of healthy tissue (left column, top layer is most superficial), a low grade squamous intraepihelial lesion (center column), and a high grade squamous intraepithelial lesion (right column) have distinctive patterns that can be automatically measured and evaluated using an algorithm for a quick diagnostic result

Credit

Dimitra Pouli, Tufts University

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