Alec Kimmelman, M.D., Ph.D., Dana-Farber Cancer Institute (IMAGE)

Dana-Farber Cancer Institute

Alec Kimmelman, M.D., Ph.D., Dana-Farber Cancer Institute

Caption

Alec Kimmelman, M.D., Ph.D., and colleagues have shown that advanced pancreatic cancers in mice are dependent on continued oncogenic Kras expression for tumor maintenance. They also report that KRAS "rewires" key metabolic pathways to fuel the cancer cells, which suggest that these altered pathways might be potential targets for future drugs.

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Sam Ogden

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