A Newly Devised Gene-editing Strategy (IMAGE)

Max Planck Florida Institute for Neuroscience

A Newly Devised Gene-editing Strategy

Caption

CRISPR/Cas9-based mutagenesis through NHEJ causes a variety of genotypes in individual cells, which make it difficult to determine the causality between genotypes and phenotypes. Steinecke et al. report a strategy for single-cell genotyping in CRISPR/Cas9-transfected neurons that were phenotypically characterized in vivo.

Credit

Max Planck Florida Institute for Neuroscience

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.