New Role for a 'Foxy Old Gene' (IMAGE)

University of Pennsylvania School of Medicine

New Role for a 'Foxy Old Gene'

Caption

Liver cells from mice that do not express FOXA2 (Mutant mice accumulated bile salts and failed to detoxify them properly, which resulted in liver damage.). The liver cells in this image show an accumulation of proteins that are used by cells to degrade unwanted substances.

Credit

Klaus Kaestner, Ph.D., University of Pennsylvania School of Medicine; Nature Medicine

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