IL‑15R‑alpha Deficiency Increases Mitochondrial Content (IMAGE)

University of Pennsylvania School of Medicine

IL‑15R‑alpha Deficiency Increases Mitochondrial Content

Caption

Muscles from mice lacking IL‑15R‑alpha and control mice were processed for presence of a mitochondrial marker. The mice lacking IL‑15R‑alpha show a greater number of darkly stained muscle fibers (right), indicating an increase in their mitochondrial content caused by reprogramming due to the lack of IL‑15R‑alpha.

Credit

Emidio E. Pistilli, PhD, & Tejvir S. Khurana, MD, PhD, Perelman School of Medicine, University of Pennsylvania. Image is based on a Figure from Pistilli et al. 2011. <i>Journal of Clinical Investigation</i>.

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