Liver Tissue (IMAGE) University of California - San Diego Caption Normal liver tissues (left) do not produce mesothelin, while liver tissue from patients with primary sclerosing cholangitis do (right, darker staining). Mesothelin is a marker of liver fibrosis, and the target of a potential new therapy for liver disease. Credit UC San Diego Health Sciences Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.