Link between 2 Key Brain Areas Involved in Schizophrenia (IMAGE)

Cold Spring Harbor Laboratory

Link between 2 Key Brain Areas Involved in Schizophrenia

Caption

The CSHL team induced PV interneurons of the medial prefrontal cortex (mPFC) to produce a red fluorescent marker that illuminates any neurons providing input to them. A direct connection is implied, therefore, with red-labeled neurons seen in this image, located in the mediodorsal thalamus (MD). Li's team has discovered an inhibitory circuit between the two brain areas that when disrupted may underlie cognitive disorders such as schizophrenia.

Credit

Li Lab, Cold Spring Harbor Laboratory

Usage Restrictions

please give credit

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.